ncRNA name | p66Shc siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human retinal endothelial cells (HRECs) |
Methods | siRNA transfection, qPCR, Western blot, immunofluorescence, chromatin immunoprecipitation (ChIP) |
Expression pattern | associated |
Functional description | P66shc-small interfering RNA (siRNA) inhibited glucose-induced Rac1 activation and mitochondrial damage. |
PubMed ID | 30105917 |
Year | 2019 |
Title | Adaptor Protein p66Shc: A Link Between Cytosolic and Mitochondrial Dysfunction in the Development of Diabetic Retinopathy. |
Drug-related ncRNA | NO |
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